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Expression of MCM6 after <t>intravitreal</t> melphalan chemotherapy in human retinoblastoma. ( A , B ) Immunohistochemical staining of MCM6 in human RB tissues from melphalan (Melp)-refractory cases ( A ) and percentage of MCM6 + cells compared with untreated RB tissues ( B ). Data are presented as mean ± SD ( n = 8 for untreated group; n = 6 for melphalan-refractory group), with significance assessed by unpaired two-tailed Student's t -test. ** P < 0.01.
Intravitreal Injection, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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intravitreal injection  (Servicebio Inc)
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Expression of MCM6 after <t>intravitreal</t> melphalan chemotherapy in human retinoblastoma. ( A , B ) Immunohistochemical staining of MCM6 in human RB tissues from melphalan (Melp)-refractory cases ( A ) and percentage of MCM6 + cells compared with untreated RB tissues ( B ). Data are presented as mean ± SD ( n = 8 for untreated group; n = 6 for melphalan-refractory group), with significance assessed by unpaired two-tailed Student's t -test. ** P < 0.01.
Intravitreal Injection, supplied by Servicebio Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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intravitreous injections  (MedChemExpress)
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Expression of MCM6 after <t>intravitreal</t> melphalan chemotherapy in human retinoblastoma. ( A , B ) Immunohistochemical staining of MCM6 in human RB tissues from melphalan (Melp)-refractory cases ( A ) and percentage of MCM6 + cells compared with untreated RB tissues ( B ). Data are presented as mean ± SD ( n = 8 for untreated group; n = 6 for melphalan-refractory group), with significance assessed by unpaired two-tailed Student's t -test. ** P < 0.01.
Intravitreous Injections, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rat ad msc ev39 dr ultracentrifugation stz induced sd rats intravitreal injection significant decrease  (System Biosciences Inc)
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Expression of MCM6 after <t>intravitreal</t> melphalan chemotherapy in human retinoblastoma. ( A , B ) Immunohistochemical staining of MCM6 in human RB tissues from melphalan (Melp)-refractory cases ( A ) and percentage of MCM6 + cells compared with untreated RB tissues ( B ). Data are presented as mean ± SD ( n = 8 for untreated group; n = 6 for melphalan-refractory group), with significance assessed by unpaired two-tailed Student's t -test. ** P < 0.01.
Rat Ad Msc Ev39 Dr Ultracentrifugation Stz Induced Sd Rats Intravitreal Injection Significant Decrease, supplied by System Biosciences Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Best corrected visual acuity (ETDRS Letters) Over Time in Innovator <t>ranibizumab</t> vs Biosimilar ranibizumab(Razumab) Groups.
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intravitreal injection  (Novartis)
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Best corrected visual acuity (ETDRS Letters) Over Time in Innovator <t>ranibizumab</t> vs Biosimilar ranibizumab(Razumab) Groups.
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avacincaptad pegol zimura intravitreal injection  (Astellas)
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Astellas avacincaptad pegol zimura intravitreal injection
Best corrected visual acuity (ETDRS Letters) Over Time in Innovator <t>ranibizumab</t> vs Biosimilar ranibizumab(Razumab) Groups.
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Expression of MCM6 after intravitreal melphalan chemotherapy in human retinoblastoma. ( A , B ) Immunohistochemical staining of MCM6 in human RB tissues from melphalan (Melp)-refractory cases ( A ) and percentage of MCM6 + cells compared with untreated RB tissues ( B ). Data are presented as mean ± SD ( n = 8 for untreated group; n = 6 for melphalan-refractory group), with significance assessed by unpaired two-tailed Student's t -test. ** P < 0.01.

Journal: Investigative Ophthalmology & Visual Science

Article Title: Targeting MCM6 Enhances Melphalan Chemosensitivity in Retinoblastoma by Modulating DNA Damage Response

doi: 10.1167/iovs.66.15.14

Figure Lengend Snippet: Expression of MCM6 after intravitreal melphalan chemotherapy in human retinoblastoma. ( A , B ) Immunohistochemical staining of MCM6 in human RB tissues from melphalan (Melp)-refractory cases ( A ) and percentage of MCM6 + cells compared with untreated RB tissues ( B ). Data are presented as mean ± SD ( n = 8 for untreated group; n = 6 for melphalan-refractory group), with significance assessed by unpaired two-tailed Student's t -test. ** P < 0.01.

Article Snippet: On day 14 post-injection, mice received a single intravitreal injection of 1-μL melphalan (0.25 μg/μL in PBS, HY-17575; MedChemExpress, Monmouth Junction, NJ, USA) or vehicle.

Techniques: Expressing, Immunohistochemical staining, Staining, Two Tailed Test

Best corrected visual acuity (ETDRS Letters) Over Time in Innovator ranibizumab vs Biosimilar ranibizumab(Razumab) Groups.

Journal: Clinical Ophthalmology (Auckland, N.Z.)

Article Title: Biosimilar Versus Innovator Ranibizumab in Myopic CNVM: Comparative Real-World Outcomes- The BRIM Study

doi: 10.2147/OPTH.S549744

Figure Lengend Snippet: Best corrected visual acuity (ETDRS Letters) Over Time in Innovator ranibizumab vs Biosimilar ranibizumab(Razumab) Groups.

Article Snippet: The study included patients diagnosed with myopic choroidal neovascular membrane (CNVM) who received intravitreal ranibizumab injections—either the innovator molecule (Lucentis/Accentrix ® , Novartis, Mumbai, India) or a biosimilar formulation (Razumab ® , Intas Pharmaceuticals Gujarat, India)—as part of their routine clinical care.

Techniques:

Central macular thickness Comparison Over Time: Innovator ranibizumab vs Biosimilar Ranibizumab (Razumab).

Journal: Clinical Ophthalmology (Auckland, N.Z.)

Article Title: Biosimilar Versus Innovator Ranibizumab in Myopic CNVM: Comparative Real-World Outcomes- The BRIM Study

doi: 10.2147/OPTH.S549744

Figure Lengend Snippet: Central macular thickness Comparison Over Time: Innovator ranibizumab vs Biosimilar Ranibizumab (Razumab).

Article Snippet: The study included patients diagnosed with myopic choroidal neovascular membrane (CNVM) who received intravitreal ranibizumab injections—either the innovator molecule (Lucentis/Accentrix ® , Novartis, Mumbai, India) or a biosimilar formulation (Razumab ® , Intas Pharmaceuticals Gujarat, India)—as part of their routine clinical care.

Techniques: Comparison